Toxoplasma hosts ROP'd into STAT3 activation
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منابع مشابه
Toxoplasma hosts ROP'd into STAT3 activation
Like cars circling city blocks on Saturday night, stem cells stand a good chance of finding a parking spot in bone marrow if they circulate long enough. Hematopoietic stem cells frequently leave their niches, freeing up space for other stem cells to enter, report Bhattacharya et al. Their finding explains a paradox posed by bone marrow transplantations that replaced recipients' blood supplies w...
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Infection by Toxoplasma gondii down-regulates the host innate immune responses, such as proinflammatory cytokine production, in a Stat3-dependent manner. A forward genetic approach recently demonstrated that the type II strain fails to suppress immune responses because of a potential defect in a highly polymorphic parasite-derived kinase, ROP16. We generated ROP16-deficient type I parasites by ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2009
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20612iti5